Department of agriculture agricultural research service. Before requesting germplasm, scientists should consider their capacity to receive it. Antimicrobial activity and phytochemistry of khaya. Citescore values are based on citation counts in a given year e. The flowers of annona genus are hermaphrodite, but the stigmas are generally not receptive at the time the pollen is shed. It is a fruit tree native to senegal and found in semiarid to subhumid regions of africa. Guide for authors phytochemistry letters issn 18743900.
Meliaceae was tested against the larvae of a one host tick, boophilus decoloratus family. Larvicidal activity of annona senegalensis and ijmrk2. Annona senegalensis, books, inflammation, leaf extract, pain, phospholipase a2, science. Medicinal plants and traditional medicine in africa abayomi. Annonaceae, plant used in burkina folk medicine to treat epilepsy and convulsions. View khaya senegalensis research papers on academia. This page was last edited on 24 august 2016, at 10. Annona muricata leaves, phytochemistry, antiinflammatory effects, anticancer effects, neurotoxic acetogenins. Isolation and structure of cyclosenegalins a and b, novel. The cytotoxicity against brine shrimp of the essential oil obtained from the leaves of annona senegalensis pers. Annonaceae, plant widely used for its therapeutic potential, the phytochemical and safety profiles of its root wood were investigated. All structured data from the file and property namespaces is available under the creative commons cc0 license. The nutritional composition of seeds fromboscia senegalensis. Annonaceae is a plant which is used in african traditional medicine for the treatment of various diseases.
Further studies on the plant may produce lead molecules for the development of new antiinflammatory drugs. The study demonstrated that khaya senegalensis stem bark aqueous extract possesses antiinflammatory activity and antinociceptive effect mediated via central and peripheral mechanisms. The aim of the present study was to report medicinal plants with psychoactive properties used to treat neuropsychiatric disorders in the hauts bassins region, in the western zone of burkina faso. Pdf phytochemical, acute and subacute toxicity studies.
Therefore, in this study the in vitro activities of the cold and hot extracts of the stem barks of the three khaya species used in the management of scd were evaluated using standard antisickling. Introduction phytochemistry letters invites rapid communications on all aspects of natural product research including. Neuropharmacological evaluation of annona senegalensis leaves. It is common throughout much of subsaharan africa, from senegal and yemen to south africa. Leaf wax of some members like annona senegalensis, was found to contain saturated and unsaturated fatty acids and primary alcohols of c28, c30 and c32. Evaluation of the acute and sub acute toxicity of annona. The structures were elucidated on the basis of the msms fragmentation, using a q. Warra aa1,umar ra2, sani i1, gafar mk3, nasiru a4, and ado a5 1dept. Distribution, phytochemistry and antioxidant properties of. Review on phytochemistry and pharmacological aspects of guiera senegalensis j. Using examples from commonly employed herbs, it explains concepts from phytochemistry and pharmacognosy that are important for understanding the characteristics. Toxicological evaluation of methanol extract of khaya. Herbal constituents is a concise yet thorough textbook for students and practitioners of botanical medicine e.
Jun 03, 2015 effect of aqueous leaf extract of annona senegalensis on selected testicular function indices of wistar rats. Three species are found along the western african region and they are khaya senegalensis ks, khaya grandifoliola kg and khaya ivorensis ki. Bioactiveguided fractionation of the methanolmethylene chloride root bark extract of a. Khaya senegalensis is a species of tree in the meliaceae family that is native to africa. Ethnopharmacological uses of erythrina senegalensis. In toxicological studies, the results indicate that the aqueous extract has a. Two new cyclopeptides, cyclosenegalin a, cyclopro 1gly 2leu 3ser 4ala 5val 6thr 7 1 and cyclosenegalin b, cyclopro 1gly 2tyr 3val 4tyr 5pro 6pro 7val 8 2, have been isolated from the methanol extract of the seeds of annona senegalensis pers. In burkina faso, phytotherapy is the main medical alternative used by populations to manage various diseases that affect the nervous system. Afromomum alboviolaceum, annona senegalensis and mondia whitei.
Phytochemical and pharmacological study of roots and leaves. Ex dc sore harouna 1, hilou adama 1, sombie pierre alexandre eric djifaby 1, compaore moussa 1, meda roland, millogo jeanne 2 and nacoulma odile germaine 1. The chemical composition of the essential oils from leaves, stems bark, roots bark, epicarp and mesocarp of these plant, growing in brazzaville congo, were analyzed by cg and cgms. Leaves of annona senegalensis yielded a sesquiterpene mixture which was reported to possess larvicidal properties 36. Compounds of methanolic fractions of ethereal leaf extract of a. Antimicrobial effects of a lipophilic fraction and. Antisickling, antioxidant and antibacterial activities of.
Erythrina senegalensis dc fabaceae, locally known as nte, is a plant that is used in traditional medicine to cure several diseases. Phytochemical and antimicrobial screening of aqueous and. Annona senegalensis fruit on a stem, with leaves near fada ngourma in burkina faso. Annona senegalensis, axonopus compressus, bryophyllum pinnatum and heliotropium indicum, which are traditionally used as medicine in southwestern part of nigeria. The major phytochemical constituents include acetogenins, alkaloids, essential oils, phenolic compounds, cyclopeptides, amino acids, pigments, and vitamins. Usda, ars, germplasm resources information network. In 2005, a survey was performed in three different regions in mali west africa to collect information on the uses of seven plants species used in traditional medicine. Foundations of phytochemistry 9780615273860 by ganora, lisa and a great selection of similar new, used and collectible books available now at great prices. Annona senegalensis, commonly known as african custardapple, wild custard apple, wild soursop, sunkungo mandinka language, and dorgot wolof language is a species of flowering plant in the custard apple family, annonaceae. This family has appreciable economic importance as a source of edible fruits. It is widely distributed throughout tanzania where it grows in wet lowland savannah by the coast, in the usambaras and in lake victoria basin.
Journal of pharmacognosy and phytochemistry preliminary phytochemical screening and physicochemical analysis of gingerbread plum parinari macrophylla seed oil. Effect of aqueous stem bark extract of khaya senegalensis on. After fractionation, nhexane and chloroform fractions of a. Toxicological evaluation of methanol extract of khaya senegalensis 559 l 1abui, oa. Annonaceae is claimed in traditional medicine in burkina faso to be useful in the treatment of epilepsy. Charles obiora nwonuma 1, emenike onyebum irokanulo 1, adeyemi eunice jolaiya 1, ayokanmi ore 2. Habitat and repartition it is a plant that grows primarily in sudanian sahel area, on soils sandy, leached or exhausted, fallow and dry stations. Jun 30, 2006 the chemical composition of total alkaloids from leaves and roots of guiera senegalensis was investigated. The in vitro toxicity of seed oil of khaya senegalensis family. Pdf phytochemical screening and antimicrobial efficacy of. Matouke2, mm in this study the mortality increased with the increment of concentration, this increment was shown to be significant p senegalensis was 8toxic to the exposed fish. Antimicrobial, phytochemistry, khaya senegalensis, roots introduction several published reports have shown the effectiveness of traditional hemicroorganisms ghani et al.
The specific epithet, senegalensis, translates to mean of senegal, the country where the type specimen was collected. National plant germplasm system covid19 update, march 23, 2020. Bohlmann and rao 106 isolated from roots of annona squamosa, 3caryophyllene 67, accompanied by several kaurane type diterpenes see below. The results of subacute toxicity study indicate that the mice receiving 300 mgkg b. Considered safe because being from natural origin, plant products can exhibit toxic effects during their use. Cytotoxic essential oil from annona sengalensis pers. With contributions from an international cast of scientists, the book details the efforts to study ethnomedicine scientifically, with topics ranging from biologically active metabolites found in. The root of guiera senegalensis is thought to possess medicinal properties according to nigerian folklore. Antimalarial and filarial mosquito vectors activity.
African journal of biochemistry research phytochemical. Annona senegalensis, also known as wild custard apple and wild soursop is a member of annonaceae family. Evaluation of antiinflammatory and antinociceptive. D06422 department of pharmacology and toxicology university of nigeria, nsukka a thesis submitted to the department of pharmacology & toxicology, faculty of pharmaceutical sciences, university of.
Review on phytochemistry and pharmacological aspects of. Probovatine, 355, recently 353 or me0 i nme me0 355 r m 355bis rh the phytochemistry of the annonaceae 2807 isolated from trunkbark of duguetia obovata, was thought to be a spirodienone related to the proerythrinadienone group 269. Effect of subchronic oral administration of aqueous stem bark extract of k. Pdf phytochemical and anticonvulsant properties of. Phytochemicals from medicinal plants are receiving ever greater attention in the scientific literature, in medicine, and in the world economy in general. The subacute toxicity studies indicated a significant p cytotoxic agent from boehmeria caudata urticaceae and cryptocarya laevigata lauraceae au hoffmann, joseph j.
Phytochemical and anticonvulsant properties of annona senegalensis pers. About 120g of the powdered samples were first defatted with nhexane for 6 hours with the aid of a soxhlet apparatus and the fat free plant material were air. A nephroprotective effect of khaya senegalensis aqueous extract was also reported. The scien tific name of this plant species was used as a. The present study was undertaken to investigate the phytochemical constituents of leaves of four medicinal plants viz. This study aimed to investigate the analgesic and antiinflammatory activity of total ethereal leaf extract fractions of a. Annonaceae is used in nigerian ethnomedicine for treatment of infectious diseases.
The diethyl ether fraction of the methanolic extract of annona senegalensis pers stem bark was prepared in yield of 0. Phytochemistry and biological activities of extracts from two. The name comes from the fact that the joints of the spider are typically coloured a golden yellow. Evaluation of phytochemicals from extract of different plant parts has results in the identification of numerous important bioactive constituents in various annona species. A wellresearched book, usually with more than one photograph of each species and good information on the plant and its uses. In this study, the phytochemical composition and invitro.
In west africa, fulani herdsmen used the stem bark and leaf of k. Phytochemistry and nutritional composition of annona senegalensis pers leaves was investigated. Phytochemical screening and antitb activity of root extracts. The seeds ofboscia senegalensisare used as a staple food during periods of famine in the sahel zone of west africa. Seeds collected in the republic of niger were extracted exhaustively with water to remove bitter components and possible toxic substances and then analyzed for their content of various nutrients. Wistar rats with renal dysfunction caused by gentamycin administration 100 mg. Pharmacological study and physicochemical characteristics of khaya senegalensis seed oil karigar asif a. Effect of aqueous leaf extract of annona senegalensis on. A small tree or shrub of the savanna of up to 6 m high, from senegal to nigeria, in the cape verde islands and across africa to sudan. Inflammation, owing to central element of innate immunity and inflammatory response serve as a protective mechanism emerged in higher animals in order to defend them against injury and infection.
The plant samples were air dried for five days and milled respectively to powder with the aid of a mechanical blender prior to extraction with the different solvents. Antisickling activities of the stem bark of three khaya. Special problems with the extraction of plants springerlink. Files are available under licenses specified on their description page. This study was undertaken to appraise the phytochemical constituents from polar and nonpolar extracts nhexane, ethyl acetate and methanol and antituberculosis activities. Annona senegalensis in the germplasm resources information network grin, u. Lipids oils and fatty acids have been isolated from the seeds and fruits of many annonaceae members. Phytochemical screening and antimicrobial efficacy of extracts from khaya senegalensis against human pathogenic bacteria article pdf available in african journal of biotechnology 724. If an internal link led you here, you may wish to change the link to point directly to the intended article.
Effect of aqueous leaf extract of annona senegalensis on selected testicular function indices of wistar rats. In accordance with statistics from the world health organization, nearly 80% of populations depend on traditional medicine for primary health care. In the present study, an ethnobotanical survey was carried out in six markets of the district of lukunga according to principles included in the declaration of helsinki. In toxicological studies, the results indicate that the aqueous extract has a low acute toxicity with an ld50 greater than 5000 mgkg b. Complete pollination seldom occurs, explaining the frequency of misshapen fruits. Read, highlight, and take notes, across web, tablet, and phone. The spider species nephila senegalensis is commonly known as the bandedlegged golden orbweb spider. The antibacterial 1 and anticancer 2 activities of extract of annona senegalensis pers. Common names include african mahogany, dry zone mahogany, gambia mahogany, khaya wood, senegal mahogany, cailcedrat, acajou, djalla, and bois rouge.
It is a fruit tree native to senegal and found in semiarid to subhumid regions of africa, with a long history of traditional use. In order to scientifically validate the phytotherapeutic wealth of the democratic republic of the congo, three plants were chosen namely. Recent journal of herbal medicine articles elsevier. Standard tube characterization tests were used to highlight phytochemical groups of root wood of the. Preparative thin layer chromatography analysis of the fraction resulted in the identification of two spots with antimicrobial activity. Phytochemistry and biological activities of extracts from two combretaceae found in burkina faso.
At present, this knowledge are being applied to other related annona species such as annona senegalensis, a. Volume 10, issue 12, december 1971, pages 32943295. Similarly, in northern nigeria the hausa utilize k. Phospholipase a2 inhibition and antiinflammatory activity. Pdf annona senegalensis, also known as wild custard apple and wild soursop is a member of annonaceae family. The phytochemical screening showed the presence of sterols and triterpens, polyphenols, reducing compounds, and flavonoids in root wood of annona senegalensis a. The plant material was identified and authenticated by mr. Phytochemical, acute and subacute toxicity studies of.
The confirmation of this toxicity has been done by using selected tumor cell lines a549, ht29, mcf 7, rpmi, and u251. Medium lethal ld 50 values of 1 296, 3 808, 1 265 and 2 154 mgkg were obtained for the mme, mf, hf and ef, respectively. Toxicity of khaya senegalensis meliaceae seed oil against. Botanical characteristics of some plant parts of sugar apple annona squamosa l. There is increasing scientific interest in the extraction and isolation of secondary metabolites from plants. Ozioko of the international centre for ethnomedicine and drug development intercedd, nsukka, enugu state, where a voucher specimen is deposited specimen number. The phytochemistry of the annonaceae sciencedirect.
875 286 463 1140 1062 808 181 1573 965 306 117 996 857 1531 553 300 855 1261 676 949 1558 953 1087 785 450 623 750 1542 1433 1410 1623 1380 1306 695 801 871 884 730 1295 1034 402 48